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30 local time (11:30 BST).
The CCTV footage appears to capture the broadcaster in the village's main street holding an umbrella roughly 20 minutes later.
A search and rescue operation, involving divers, helicopters, and drones, was called off by Greek authorities at 20:00 on Friday evening.
Officials are now understood to be excluding the possibility that Dr.
Mosley came to harm while walking between the beach and Pedi.
The search and rescue operation had previously been focused on a rocky coastal path between the beach and Pedi that Dr.
Mosley was thought to have taken.
The BBC has seen a second piece of CCTV footage from a nearby premises showing a man wearing the same clothes and carrying the same umbrella, which was timestamped at 13:50.
A woman said she had seen Dr.
Mosley in Pedi on Wednesday, the island's deputy mayor Ilias Chaskas told BBC News.
Taking part in the search, Dr.
Chaskas said they have 'looked everywhere,' and divers had been 'looking into the water' with the help of the Hellenic Coast Guard.
Symi's coast guard said all patrol boats, private boats, and commercial boats near the island had been searching for Dr.
Mosley.
'Everybody is worried and looking for him,' said Mika Papakalodouka, daughter of the mayor of Symi, Eleftherios Papakalodouka.
The search party currently consists of 25 people, including police officers, divers, volunteers, and firefighters.
Greek police said Dr.
Mosley left his wife Clare on the beach before setting off on a walk to the center of the island on Wednesday.
His phone was found where he was staying with his wife, who reported him missing, a police spokesperson told BBC News.
His three adult sons and one daughter have flown to the island to join the search, Dr.
Mosley’s brother Arthur told The Telegraph on Friday.
After officers on the island were unable to find Dr.
Mosley, they requested help from the Greek fire department in Athens.
Firefighters arrived in Symi from nearby Rhodes at 14:00 on Thursday.
An appeal saying he was missing was posted on a local Facebook group on Wednesday, alongside a picture of Dr.
Mosley wearing a blue cap, polo shirt, and shorts.
'Have you seen this man? He set off to walk back from [Agios Nikolaos beach] at about 13:30 and failed to make it home,' it said.
It was extremely hot on the island on Wednesday, with the National Observatory of Athens reporting temperatures of more than 40°C at 15:00.
Symi is part of Greece's Dodecanese island group and sits about 12 miles (19 km) northwest of Rhodes.
In the 2021 census, it had a population of approximately 2,600 people.
Father and daughter Antonis and Maria, who have lived on Symi all their lives, said his disappearance is shocking and confusing.
With temperatures forecast to reach around 37°C on Friday, a yellow high-temperature warning has been issued across the island of Symi.
The combination of the sweltering weather and rugged terrain will make the task for those searching for Dr.
Mosley even more challenging.
A Foreign Office spokesperson said: 'We are supporting the family of a British man who is missing in Greece and are in contact with the local authorities.
' Before moving into TV, Dr.
Mosley studied medicine in London and qualified as a doctor, but for the last couple of decades has been working as a presenter, documentary maker, journalist, and author.
He writes a column for the Daily Mail and his TV programmes also include Channel 4 show 'Michael Mosley: Who Made Britain Fat?' Dr.
Mosley has been an advocate for intermittent fasting diets, including the 5:2 diet and The Fast 800 diet.
He has four children with his wife Clare Bailey Mosley, who is also a doctor, author, and healthy living advocate.
The couple recently appeared at the Hay Festival where Dr.
Mosley presented a special edition of BBC Radio 4's 'Just One Thing.
' Reacting to the 'shocking news,' his fellow 'Trust Me, I'm A Doctor' co-star Dr.
Saleyha Ahsan said she was 'praying he is found safe' and she feels 'sick with worry.
' On Thursday's edition of 'The One Show,' presenter Alex Jones opened the programme by expressing concern that 'our friend' had gone missing.
'Our thoughts are very much with his wife Clare and the rest of his family at this worrying time.
We hope for more positive news,' she added.